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A INOVE Oftalmologia parabeniza o Dr. Rafael Miranda Sousa pela publicação do artigo original referente aos dados da sua pesquisa de doutorado na Investigative Ophthalmology & Visual Science (IOVS) revista científica da The Association for Research in Vision and Ophthalmology (ARVO) – Academia Americana de Pesquisa em Oftalmologia, um dos mais importantes periódicos científicos de oftalmologia do mundo.
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Resumo do artigo publicado e acesso a integra do artigo no link abaixo:
Multifocal Visual Evoked Potential in Eyes With
Temporal Hemianopia From Chiasmal Compression:
Correlation With Standard Automated Perimetry and
To verify whether multifocal visual evoked potential (mfVEP) can differentiate eyes with temporal hemianopia due to chiasmal compression from healthy controls. To assess the relationship between mfVEP, standard automated perimetry (SAP), and Fourier domain-optical coherence tomography (FD-OCT) macular and peripapillary retinal nerve fiber layer (RNFL) thickness measurements.
Twenty-seven eyes with permanent temporal visual field (VF) defects from chiasmal compression on SAP and 43 eyes of healthy controls were submitted to mfVEP and FD-OCT scanning. Multifocal visual evoked potential was elicited using a stimulus pattern of 60 sectors and the responses were averaged for the four quadrants and two hemifields. Optical coherence tomography macular measurements were averaged in quadrants and halves, while peripapillary RNFL thickness was averaged in four sectors around the disc. Visual field loss was estimated in four quadrants and each half of the 24-2 strategy test points. Multifocal visual evoked potential measurements in the two groups were compared using generalized estimated equations, and the correlations between mfVEP, VF, and OCT findings were quantified.
Multifocal visual evoked potential-measured temporal P1 and N2 amplitudes were significantly smaller in patients than in controls. No significant difference in amplitude was observed for nasal parameters. A significant correlation was found between mfVEP amplitudes and temporal VF loss, and between mfVEP amplitudes and the corresponding OCT-measured macular and RNFL thickness parameters.
Multifocal visual evoked potential amplitude parameters were able to differentiate eyes with temporal hemianopia from controls and were significantly correlated with VF and OCT findings, suggesting mfVEP is a useful tool for the detection of visual abnormalities in patients with chiasmal compression.
- PMID:28863215 DOI:10.1167/iovs.17-21529